
TidalSense was founded in Cambridge in 2013 and is led by chief executive Dr Ameera Patel, a physician and engineer, alongside co-founder and chief engineering officer Julian Carter. Its N-Tidal device reads the carbon dioxide waveform of ordinary tidal breathing, so a patient breathes normally into a handheld sensor for 75 seconds instead of performing the forced manoeuvre spirometry demands, and machine learning models classify the resulting curve. A clinician can assess four to six patients an hour rather than roughly one, and any healthcare professional can run the test after ten minutes of training. In March 2025 N-Tidal Diagnose became the first non-spirometry AI diagnostic device to receive CE marking under EU MDR (Class IIa) for COPD. It entered NHS service in September 2025 and has raised $40M in total, including $11M in grants and a $19M round led by Cross-Border Impact Ventures in July 2026.
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